32 Kühn, Anne Koch, Iring Publikationsserver der RWTH Aachen University Aachen German 260 S. : Ill., graph. Darst. In daily life, we are enclosed by constantly changing structures. We perceive and learn to appreciate these so called stimulus sequences in order to appropriately adapt our behavior. For example, a step onto a moving escalator is exactly planned to avoid stumbling. But in case of an escalator not moving, the planning of the step has to be altered and adapted to the new situation. Such an adaptation of well experienced behavior is necessary after breaches of expectancy. In this dissertation, functional magnetic resonance imaging (fMRI) studies observe neural correlates of reorientation within well-known stimulus sequences after breaches of expectancy of different strength, and, of temporally remote effects after such breaches of expectancy. Moreover, it is described which cortical areas allow to efficiently predict long and hierarchically structured stimulus sequences. Data show that especially the activation of the frontopolar cortex (Brodmann Area (BA 10)) correlates with the hierarchical order of to-be-predicted stimulus sequences. While the temporally remote effect after breaches of expectancy is reflected in an attenuation of the dorsal frontomedian activity (BA 9m), the immediate reorientation, i.e. search for appropriate prediction, is reflected in activation of a complex cortical network. Thereby the (median) parietal areas can be interpreted as a regulating interface between the top-down information of prefrontal areas and bottom-up information of temporal areas. Furthermore, the anterior ventrolateral prefrontal cortex is activated the more, the less reorientation was necessary. Zsfassung in dt. und engl. Sprache. - Prüfungsjahr: 2011. - Publikationsjahr: 2012 ; Aachen, Techn. Hochsch., Diss., 2011 ; PUB:(DE-HGF)11, ; 2, ; Kognition Funktionelle NMR-Tomographie Chunking Erwartung Episodisches Gedächtnis Explizites Gedächtnis Präfrontaler Cortex Anpassung Abruf Dissertation / PhD Thesis 2011 RWTH-CONV-124391 2011 http://publications.rwth-aachen.de/record/62904