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Advancing 3D borylated molecules for revolutionary synthesis. The development of borylated molecules plays a vital role in molecular construction for both academia and industry, aiding processes like the Nobel Prize-winning Brown oxidation and Suzuki-Miyaura cross-coupling. These molecules are used in organic synthesis, but creating C-B bonds at sp3 carbons remains a challenge. The pharmaceutical industry recognises the clinical advantages of 3D molecules, fuelling efforts to develop synthetic methods. However, strategies to deliver stable, modular building blocks for diversified cross-coupling reactions remain limited. Supported by the Marie Skłodowska-Curie Actions programme, the BRADOCO project will introduce innovative boryl radical precursors. This will enable the generation of unique 3D borylated molecules for modular cross-coupling, opening up new possibilities for creating materials otherwise unattainable.
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