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@PHDTHESIS{Fan:1013719,
author = {Fan, Jilin},
othercontributors = {Herrmann, Andreas and De Laporte, Laura},
title = {{U}ltrasound-induced polymer mechanochemistry enabling
molecule release},
school = {RWTH Aachen University},
type = {Dissertation},
address = {Aachen},
publisher = {RWTH Aachen University},
reportid = {RWTH-2025-05662},
pages = {1 Online-Ressource : Illustrationen},
year = {2025},
note = {Veröffentlicht auf dem Publikationsserver der RWTH Aachen
University; Dissertation, RWTH Aachen University, 2025},
abstract = {This thesis investigates ultrasound-induced molecule
release in various polymer systems. In Chapter 2,
ultrasound-induced drug release from microcapsules was
investigated. We found that within 10 min of ultrasonic
treatment, $80\%$ of the nanodrug was released from the
polyelectrolyte microcapsules, and about $30\%$ from silica
capsules. In Chapter 3, I synthesized the network core star
polymers. In this study, disulfide mechanophores were
incorporated into the network core, and we found that the
mechanophore activation rate in network core star polymers
is faster than in linear polymers. In Chapter 4, I prepared
microgels with an average size of around 400 nm. In this
study, we found that approximately $27\%$ of the probe
molecules were released from the microgels after 20 minutes
of 0.66 MHz irradiation. In Chapter 5, I prepared the
polymeric microbubbles. The average size is around 30 μm.
Ultrasound-induced diverse mechanophores activation in
microbubbles was investigated, including disulfide
mechanophore, furylcarbinol Diels-Alder adduct, and
flex-mechanophore.},
cin = {155910 / 150000 / 052200},
ddc = {540},
cid = {$I:(DE-82)155910_20190516$ / $I:(DE-82)150000_20140620$ /
$I:(DE-82)052200_20140620$},
typ = {PUB:(DE-HGF)11},
doi = {10.18154/RWTH-2025-05662},
url = {https://publications.rwth-aachen.de/record/1013719},
}