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@PHDTHESIS{Loh:1013853,
      author       = {Loh, Johnson Luo},
      othercontributors = {Gemmeke, Tobias and Schmeink, Anke},
      title        = {{N}euro-inspired hardware acceleration for efficient
                      biomedical signal processing in mobile sensing devices},
      school       = {Rheinisch-Westfälische Technische Hochschule Aachen},
      type         = {Dissertation},
      address      = {Aachen},
      publisher    = {RWTH Aachen University},
      reportid     = {RWTH-2025-05740},
      pages        = {1 Online-Ressource : Illustrationen},
      year         = {2025},
      note         = {Veröffentlicht auf dem Publikationsserver der RWTH Aachen
                      University; Dissertation, Rheinisch-Westfälische Technische
                      Hochschule Aachen, 2025},
      abstract     = {The processing of biomedical signals in mobile sensing
                      devices enables the continuous monitoring of health
                      parameters for early detection of threatening arrhythmia in
                      the population through convenient wearable devices, such as
                      smartwatches. The design of processing modules, which are
                      feasible in this resource-constrained environment, is
                      subject to multiple constraints for their deployment
                      in-field. High quality classification is desired for
                      accurate detection to trigger treatment by trained
                      personnel. Robust classification beyond available training
                      data is necessary to generalize system feasibility across
                      the general population. Low-power operation is necessary for
                      long-termscreening for sparse features indicating abnormal
                      health conditions. The co-optimization of neuro-inspired
                      algorithms on dedicated hardware shows the promise to
                      address all desired specifications in an
                      application-specific device. This work explores
                      neuro-inspired concepts for low-power digital processing of
                      biomedical signals. Artificial neural networks has shown
                      superior classification capabilities in the machine learning
                      domain. Using an artifical neural network as a baseline, a
                      systematic design space exploration methodology is applied
                      to design an ECG classifier and co-optimize the system from
                      the algorithm level down to a hardware design for ultra-low
                      power consumption and high classification quality. Then, the
                      system is extended with a domain generalization method for
                      robust classification across multiple datasets. The method
                      is designed for direct integration into a pre-trained neural
                      network with low overhead regarding inference and training.
                      At last, the temporal coding of information in spikes is
                      adopted from the human brain as a data processing mechanism
                      for low power processing. The investigated temporal coding
                      method shows equivalent numerical values after processing
                      with reduced operations compared to conventional fixed-point
                      arithmetic. In the end, the neuro-inspired concepts show
                      promising directions to improve specialized ANN hardware
                      accelerators for biomedical signal processing both for
                      low-power processing and robust high-quality
                      classification.},
      cin          = {611110},
      ddc          = {621.3},
      cid          = {$I:(DE-82)611110_20170101$},
      typ          = {PUB:(DE-HGF)11},
      doi          = {10.18154/RWTH-2025-05740},
      url          = {https://publications.rwth-aachen.de/record/1013853},
}