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TY  - THES
AU  - Stollenwerk, André
TI  - Ein modellbasiertes Sicherheitskonzept für die extrakorporale Lungenunterstützung
VL  - 2013,7
CY  - Aachen
PB  - Shaker
M1  - RWTH-CONV-144193
T2  - Aachener Informatik-Berichte
SP  - XX, 183 S. : Ill., graph. Darst.
PY  - 2013
N1  - Zsfassung in dt. und engl. Sprache
N1  - Zugl.: Aachen, Techn. Hochsch., Diss., 2013
AB  - Extracorporeal lung assist (ECLA) is currently used as a last resort in the treatment of acute respiratory distress syndrome (ARDS). This is not least due to the complexity of the application and the associated risks. To overcome this drawback, the SmartECLA project has been carried out with the aims of applying constructive design improvements to the ECLA and also establishing a control and safety concept. This thesis elaborates on a safety concept for a patient-centered, controlled ECLA. A system analysis that recognizes errors and helps estimate the system state, based on a Failure Mode and Effects Analysis (FMEA) as well as Fault Tree Analysis (FTA), was initially carried out. Models were developed, which specifically detect continuous processes and monitor the condition of the used oxygenator or recirculation within the vena cava of the patient caused by extracorporeal circulation, as well as discrete events such as the suction of the discharging vessel wall to the cannula or deviations of the blood pump behavior from the expected pattern, e. g. caused by gas in the bloodstream. The developed models selectively substantiate the previously identified potential sources of errors. Thus, patient safety can be ensured should components malfunction. This safety concept is implemented on a network of distributed safety nodes using an elaborated software architecture. This architecture enables efficient assessment, and hence sound planning of the available resources. This predictability is achieved by data management in the system concept based on a static data module, which only projects the data structures and algorithms in code required due to embedded applications. Various development paths are simultaneously supported, thus new models and applications can be mapped efficiently. The developed system setup is based on a modular structured and electrically robust hardware platform that can be adapted to the specific application needs. Hence, energy consumption, costs and development costs can be minimized. One further development based on the designed hardware platform is the developed console to control the utilized diagonal blood pump with integrated blood flow control unit. The results presented in this thesis are a part of the essential innovations, which enabled a proof-of-concept for the sound conduct of an automated ECLA.
KW  - ARDS (SWD)
KW  - Blutpumpe (SWD)
KW  - Eingebettetes System (SWD)
KW  - Extrakorporale Membranoxygenation (SWD)
KW  - Hardware (SWD)
KW  - Lungenunterstützung (SWD)
KW  - Medizintechnik (SWD)
KW  - Sicherheit (SWD)
KW  - extrakorporale Lungenunterstützung (SWD)
LB  - PUB:(DE-HGF)11 ; PUB:(DE-HGF)3
UR  - https://publications.rwth-aachen.de/record/229222
ER  -