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@PHDTHESIS{Stollenwerk:229222,
author = {Stollenwerk, André},
othercontributors = {Kowalewski, Stefan},
title = {{E}in modellbasiertes {S}icherheitskonzept für die
extrakorporale {L}ungenunterstützung},
volume = {2013,7},
address = {Aachen},
publisher = {Shaker},
reportid = {RWTH-CONV-144193},
series = {Aachener Informatik-Berichte},
pages = {XX, 183 S. : Ill., graph. Darst.},
year = {2013},
note = {Zsfassung in dt. und engl. Sprache; Zugl.: Aachen, Techn.
Hochsch., Diss., 2013},
abstract = {Extracorporeal lung assist (ECLA) is currently used as a
last resort in the treatment of acute respiratory distress
syndrome (ARDS). This is not least due to the complexity of
the application and the associated risks. To overcome this
drawback, the SmartECLA project has been carried out with
the aims of applying constructive design improvements to the
ECLA and also establishing a control and safety concept.
This thesis elaborates on a safety concept for a
patient-centered, controlled ECLA. A system analysis that
recognizes errors and helps estimate the system state, based
on a Failure Mode and Effects Analysis (FMEA) as well as
Fault Tree Analysis (FTA), was initially carried out. Models
were developed, which specifically detect continuous
processes and monitor the condition of the used oxygenator
or recirculation within the vena cava of the patient caused
by extracorporeal circulation, as well as discrete events
such as the suction of the discharging vessel wall to the
cannula or deviations of the blood pump behavior from the
expected pattern, e. g. caused by gas in the bloodstream.
The developed models selectively substantiate the previously
identified potential sources of errors. Thus, patient safety
can be ensured should components malfunction. This safety
concept is implemented on a network of distributed safety
nodes using an elaborated software architecture. This
architecture enables efficient assessment, and hence sound
planning of the available resources. This predictability is
achieved by data management in the system concept based on a
static data module, which only projects the data structures
and algorithms in code required due to embedded
applications. Various development paths are simultaneously
supported, thus new models and applications can be mapped
efficiently. The developed system setup is based on a
modular structured and electrically robust hardware platform
that can be adapted to the specific application needs.
Hence, energy consumption, costs and development costs can
be minimized. One further development based on the designed
hardware platform is the developed console to control the
utilized diagonal blood pump with integrated blood flow
control unit. The results presented in this thesis are a
part of the essential innovations, which enabled a
proof-of-concept for the sound conduct of an automated
ECLA.},
keywords = {ARDS (SWD) / Blutpumpe (SWD) / Eingebettetes System (SWD) /
Extrakorporale Membranoxygenation (SWD) / Hardware (SWD) /
Lungenunterstützung (SWD) / Medizintechnik (SWD) /
Sicherheit (SWD) / extrakorporale Lungenunterstützung
(SWD)},
cin = {120000 / 122810},
ddc = {620},
cid = {$I:(DE-82)120000_20140620$ / $I:(DE-82)122810_20140620$},
typ = {PUB:(DE-HGF)11 / PUB:(DE-HGF)3},
urn = {urn:nbn:de:hbz:82-opus-47643},
url = {https://publications.rwth-aachen.de/record/229222},
}
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