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@PHDTHESIS{Hristeva:571844,
author = {Hristeva, Stanimira},
othercontributors = {Enders, Dieter and Albrecht, Markus},
title = {{D}evelopment of new asymmetric organocatalytic domino
reactions for the synthesis of (benzo-fused) five- and
benzo-fused six-membered cyclic compounds},
school = {RWTH Aachen},
type = {Dissertation},
address = {Aachen},
reportid = {RWTH-2016-02350},
pages = {135 Seiten : Illustrationen},
year = {2015},
note = {Veröffentlicht auf dem Publikationsserver der RWTH Aachen
University; Dissertation, RWTH Aachen, 2015},
abstract = {The present dissertation reports the work performed in the
field of organocatalyzed domino reactions. The work can be
divided into four projects. The first project included the
development of a Michael/Michael domino reaction for the
construction of polysubstituted
1,2,3,4-tetrahydronaphthalenes through the reaction between
2-(nitromethyl)nitrostyrene and α,β-unsaturated aldehydes
successfully promoted by TMS-protected diphenylprolinol. In
the second project a new asymmetric organocatalyzed domino
reaction for the construction of 4,5-disubstituted
3-hydroxy-1H-pyrrol-2(5H)-ones was developed. The Brønsted
base cupreine successfully facilitated the
Mannich/cyclization cascade sequence between α-ketoesters
and aldimines. Next, the reaction between the
o-divinylketone and 3-phenylpropanal in conditions of
secondary amine organocatalysis was investigated. In the
last project, an enantioselective organocatalytic
Friedel-Crafts-type Michael addition of electron-rich arenes
to nitroolefins was studied.},
cin = {152110 / 150000},
ddc = {540},
cid = {$I:(DE-82)152110_20140620$ / $I:(DE-82)150000_20140620$},
typ = {PUB:(DE-HGF)11},
urn = {urn:nbn:de:hbz:82-rwth-2016-023506},
doi = {10.18154/RWTH-2016-02350},
url = {https://publications.rwth-aachen.de/record/571844},
}