A novel autosomal recessive TERT T1129P mutation in a dyskeratosis congenita family leads to cellular senescence and loss of CD34+ hematopoietic stem cells not reversible by mTOR-inhibition

Stockklausner, Clemens; Hofmann, Wolf-Karsten; Kulozik, Andreas E.; Bürger, Friederike; Beier, Fabian; Trumpp, Andreas; Luke, Brian; Korbel, Jan O.; Rausch, Tobias; Tagliaferri, Laura; Sauer, Sven W.; Nowak, Daniel; Brümmendorf, Tim Henrik; Buergermeister, Rebecca; Klermund, Julia; Hoffmann, Georg F.; Bandapalli, Obul Reddy; Raffel, Simon; Kerber, Carolin; Lorenz, Holger

doi:10.18154/RWTH-CONV-092628

TY  - JOUR
AU  - Stockklausner, Clemens
AU  - Raffel, Simon
AU  - Klermund, Julia
AU  - Bandapalli, Obul Reddy
AU  - Beier, Fabian
AU  - Brümmendorf, Tim Henrik
AU  - Bürger, Friederike
AU  - Sauer, Sven W.
AU  - Hoffmann, Georg F.
AU  - Lorenz, Holger
AU  - Tagliaferri, Laura
AU  - Nowak, Daniel
AU  - Hofmann, Wolf-Karsten
AU  - Buergermeister, Rebecca
AU  - Kerber, Carolin
AU  - Rausch, Tobias
AU  - Korbel, Jan O.
AU  - Luke, Brian
AU  - Trumpp, Andreas
AU  - Kulozik, Andreas E.
TI  - A novel autosomal recessive TERT T1129P mutation in a dyskeratosis congenita family leads to cellular senescence and loss of CD34+ hematopoietic stem cells not reversible by mTOR-inhibition
JO  - Aging: open-access Impact journal on aging
VL  - 7
IS  - 11
SN  - 1945-4589
CY  - [S.l.]
PB  - Impact Journals, LLC
M1  - RWTH-CONV-092628
SP  - 911-927
PY  - 2015
LB  - PUB:(DE-HGF)16
UR  - <Go to ISI:>//WOS:000366369700007
C6  - pmid:26546739
DO  - DOI:10.18632/aging.100835
UR  - https://publications.rwth-aachen.de/record/572124
ER  -

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