% IMPORTANT: The following is UTF-8 encoded. This means that in the presence
% of non-ASCII characters, it will not work with BibTeX 0.99 or older.
% Instead, you should use an up-to-date BibTeX implementation like “bibtex8” or
% “biber”.
@PHDTHESIS{GhoshHeiringhoff:61097,
author = {Ghosh-Heiringhoff, Natalie},
othercontributors = {Dahl, Jürgen vom},
title = {{K}linische und angiographische {A}kut- und
{L}angzeitergebnisse nach direkter {S}tentimplantation bei
{P}atienten mit symptomatischer koronarer {H}erzkrankheit},
address = {Aachen},
publisher = {Publikationsserver der RWTH Aachen University},
reportid = {RWTH-CONV-122780},
pages = {86 S. : Ill., graph. Darst.},
year = {2006},
note = {Aachen, Techn. Hochsch., Diss., 2006},
abstract = {The study presented the acute- and long- time results of
patients with coronary artery disease who undergo direct
stent implantation. The values are resulted on one side from
digital quantitative coronary coronarangiography (QCA) and
on the other side from the clinical symptoms classified by
the Canadian Cardiovascular Society (CCS) and the New York
Heart Association (NYHA).Angiographic results:The proximal,
mean and distal reference diameter did not vary between the
various measurements. The minimal lumen diameter (MLD)
increased from 0.8 (SD 0.4) mm up to 2.5 (SD 0.8) mm. This
corresponds with an acute gain of 1.6 (SD 0.8) mm. At the
follow-up was the value of MLD 1.6 (SD 0.8) mm, resulting a
late loss of 0.5 (SD 0.9) mm. The net gain was 1.1 (SD 0.7)
mm. The mean diameter of stenosis correlates similar to the
MLD. The length of stenosis was quantified with 9.5 (SD 4.1)
mm. The mean ballon diameter was 3.0 (SD 0.4) mm. The mean
diameter of stenosis after intervention was calculated with
$14\%,$ after round about 6 months with $28\%.$ In 46 cases
$(28\%)$ a new stenosis in the stent area could be detected.
In a group of 20 patients $(43\%)$ remained a restenosis (>
$50\%$ diameter of stenosis).Clinical results:Our patients
had a lot of angiographic characteristics which come along
with an increased risk of a worse outcome. Especially this
relates to the high incidence of multivessel-disease and
complex with partly thrombus containing stenosis (type B2 /
C). Despite of this, the results from the digital
quantitative coronarangiography and the clinical outcomes
showed a very good angiographic and clinical output after
direct stent implantation. $92\%$ of the patients (n= 151)
were significantly relieved of their symptoms and 1/3 was
completely without any symptoms.The data analysis showed
that the clinical outcomes of the patients differed often
from the angiographic results of the therapied lesions. The
target vessel minimal lumen diameter (MLD) of the patients
with permanent angina pectoris or dyspnoe symtoms did not
differ from those who had not any clinical symptoms (2.0 (SD
0.7) mm vs. 2.0 (SD 0.7) mm). $70\%$ of these patients had a
multivessel-disease. All stents with one exception offered
an excellent angiographic result (mean diameter stenosis of
$32\%)$ at the follow-up.28 patients $(17\%)$ were
hospitalised because of cardiological reasons, $86\%$ had
symptoms of angina pectoris. In 25 cases the follow-up was
brought forward. $80\%$ out of it had an excellent result of
the stent (mean diameter of stenosis $30.4\%).$ In case of
16 patients the angina pectoris symptoms were caused by
stenosis outside of the target vessel, in 11 cases occured a
Re-PTCA, in the other cases was a drug orientated concept
established.In the meantime in 4 cases $(2\%)$ happened an
acute coronary syndrome (ACS). In 3 of it were the target
vessel involved, but only by one patient was the reason
located in the stent. In the other cases the ACS was caused
by a subtotal stenosis distal the direct implanted stent
(>/=5 mm). In more than one third of the cases in which the
follow-up was brought forward, a reintervention happened.
But only by $8\%$ of the patients, who came to the regular
follow-up, was a new intervention necessary. In total, at
the regular follow-up in 25 cases $(15\%)$ a reintervention
occured. By 13 Patienten $(8\%)$ was the target vessel (TVR)
involved.At the analysis of potential predictors, which
favoured restenosis, only some trends could be found. These
correlated with the aspects which are described in the
literature. For example long or complex lesions (type B / C)
have promoted effects to the process of restenosis. The same
for diabetes mellitus.Conclusion:The studie showed that in a
great collective of stenosed lesions a very good
angiographic and clinical outcome could be achieved.But the
restenosis is independent from the kind of the stent
implantation the Achilles tendon of the coronary
angioplastie.},
keywords = {Implantation (SWD) / Koronarendoprothese (SWD) / Stent
(SWD) / Kardiologie (SWD) / Angiokardiographie (SWD) /
Koronarographie (SWD) / Koronare Herzkrankheit (SWD) /
Kardiovaskuläre Krankheit (SWD)},
cin = {510000-1},
ddc = {610},
cid = {$I:(DE-82)510000-1_20140620$},
typ = {PUB:(DE-HGF)11},
urn = {urn:nbn:de:hbz:82-opus-14915},
url = {https://publications.rwth-aachen.de/record/61097},
}
guest ::