h1

h2

h3

h4

h5
h6
% IMPORTANT: The following is UTF-8 encoded.  This means that in the presence
% of non-ASCII characters, it will not work with BibTeX 0.99 or older.
% Instead, you should use an up-to-date BibTeX implementation like “bibtex8” or
% “biber”.

@PHDTHESIS{Fischer:61176,
      author       = {Fischer, Robert},
      othercontributors = {Rossaint, Rolf},
      title        = {{N}arkosekomplikationen im {S}äuglingsalter : eine
                      retrospektive {V}ergleichsstudie zwischen
                      {I}ntubationsnarkose und {S}pinalanästhesie an
                      {S}äuglingen mit {L}eistenhernienoperationen unter
                      besonderer {B}erücksichtigung postoperativer {A}pnoephasen},
      address      = {Aachen},
      publisher    = {Publikationsserver der RWTH Aachen University},
      reportid     = {RWTH-CONV-122856},
      pages        = {77 S. : Ill., graph. Darst.},
      year         = {2006},
      note         = {Aachen, Techn. Hochsch., Diss., 2006},
      abstract     = {Subject of this study was to compare general anaesthesia
                      and spinal anaesthesia in infants. Anaesthetic complications
                      and postoperative apnea were discovered and subsequently
                      compared refer to the anaesthetic technique. For that
                      purpose the patient records of all infants undergoing
                      inguinal hernia repair at University Hospital Aachen between
                      1997 and 2003 were collected and examined retrospectively.
                      Altogether 275 infants could be included in this study of
                      which 166 received general anaesthesia (ITN group) and 109
                      received spinal anaesthesia (SPA group). For general
                      anaesthesia muscle relaxants were used at introduction,
                      volatile anaesthetics were used for maintenance in $95\%$
                      (including $65\%$ Sevofluran) and for intraoperativ
                      analgesia opioid (Fentanyl, Piritramid) was used in 2/3 of
                      the patients. For spinal anaesthesia only isobaric
                      Bupivacaine $0.5\%$ in dosage 1 mg/kg (body weight minus
                      $10\%)$ was injected. The comparisons of pre-existing
                      conditions of the infants refer to the chosen anaesthetic
                      technique showed significant statistical differences: The
                      infants in SPA group had a lower birth weight and have been
                      born in earlier pregnancy, at operation the postmenstrual
                      age and body weight was lower; also a higher grade of
                      comorbidity was demonstrated. For summary the infants in SPA
                      group had already preoperative a higher disposition to
                      develop perioperative complications or postoperative apnea.
                      Postoperative apnea was detected by respiration monitors
                      and/or monitoring of peripheral oxygen saturation.
                      Intraoperative anaesthetic complications was analysed
                      separately from apnea complications: Within the ITN group
                      $16.9\%$ of the infants demonstrated intraoperative
                      anaesthetic complications whereas in SPA group none was
                      described (p=0.000). Postoperative new occurred apnea was
                      demonstrated by 14 infants of ITN group and one infant of
                      SPA group (p=0.020). The analysis of subgroups (infants
                      after postpartal respirator-therapy (n=66), infants with
                      pulmonal diseases (n=73), ex-premature infants (n=142),
                      infants with less than 1500g birth weight (n=67)) showed
                      significant advantages for the use of spinal anaesthesia.
                      Critical analysis of already published studies concerning
                      anaesthetic complications and postoperative apnea in infants
                      demonstrates great variability but in all more complications
                      and higher incidence of postoperative apnea in general
                      anaesthesia. The risk of anaesthetic complications or
                      postoperative apnea is lower in spinal anaesthesia compared
                      to general anaesthesia, but even after spinal anaesthesia
                      postoperative apnea can occur, which is important concerning
                      ambulatory surgery and postoperative monitoring. For
                      conclusion this study shows that spinal anaesthesia can be
                      recommended as a save and effective anaesthetic technique
                      especially in high-risk infants with pre-existing diseases.},
      cin          = {510000-1},
      ddc          = {610},
      cid          = {$I:(DE-82)510000-1_20140620$},
      typ          = {PUB:(DE-HGF)11},
      urn          = {urn:nbn:de:hbz:82-opus-15169},
      url          = {https://publications.rwth-aachen.de/record/61176},
}