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%0 Thesis
%A Meißner, Lena Elisabeth
%T Monitoring, characterizing, and influencing the poly(γ-glutamic acid) production by Bacillus licheniformis
%I Rheinisch-Westfälische Technische Hochschule Aachen
%V Dissertation
%C Aachen
%M RWTH-2016-05266
%P 1 Online Ressource (XVIII, 118 Seiten) : Illustrationen
%D 2016
%Z Veröffentlicht auf dem Publikationsserver der RWTH Aachen University
%Z Dissertation, Rheinisch-Westfälische Technische Hochschule Aachen, 2016
%X Bacillus spp. are used for the production of industrial enzymes, such as proteases for the detergent industry, but are also known to be capable of producing biopolymers such as poly(γ-glutamic acid) (γ-PGA). Biopolymers increase the viscosity of the fermentation broth, thereby impairing mixing, gas/liquid mass transfer, and heat transfer in any bioreactor system. Undesired biopolymer formation has a significant impact on fermentation and downstream processing performance, respectively. The first part of this thesis shows how undesirable γ-PGA formation of an industrial protease producing Bacillus licheniformis strain (A1) was prevented by switching the nitrogen source from ammonium to nitrate. The maximum viscosity at a shear rate of 300 s-1 was reduced by over 90 
%F PUB:(DE-HGF)11
%9 Dissertation / PhD Thesis
%U https://publications.rwth-aachen.de/record/660263