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000773440 001__ 773440 000773440 005__ 20230408050112.0 000773440 0247_ $$2HBZ$$aHT020278137 000773440 0247_ $$2Laufende Nummer$$a38633 000773440 037__ $$aRWTH-2019-11105 000773440 041__ $$aEnglish 000773440 082__ $$a610 000773440 1001_ $$0P:(DE-588)1199210137$$aHermanspann, Theresa$$b0$$urwth 000773440 245__ $$aEvaluation of the medication process of intravenous preparations in two intensive care units$$cvorgelegt von Theresa Hermanspann$$hprint 000773440 260__ $$aAachen$$c2019 000773440 300__ $$a1 Band (verschiedene Zählungen) : Illustrationen, Diagramme 000773440 3367_ $$02$$2EndNote$$aThesis 000773440 3367_ $$0PUB:(DE-HGF)11$$2PUB:(DE-HGF)$$aDissertation / PhD Thesis$$bphd$$mphd 000773440 3367_ $$2BibTeX$$aPHDTHESIS 000773440 3367_ $$2DRIVER$$adoctoralThesis 000773440 3367_ $$2DataCite$$aOutput Types/Dissertation 000773440 3367_ $$2ORCID$$aDISSERTATION 000773440 502__ $$aDissertation, Rheinisch-Westfälische Technische Hochschule Aachen, 2019, Kumulative Dissertation$$bDissertation$$cRheinisch-Westfälische Technische Hochschule Aachen$$d2019$$gFak10$$o2019-09-18 000773440 5203_ $$lger 000773440 520__ $$aPurpose: To determine the type, frequency, and factors associated with medication preparationand administration errors in adult intensive care units (ICUs) and neonatal ICUs (NICUs)/pediatric ICUs (PICUs).Patients and methods: We conducted a prospective direct observation study in an adultICU and NICU/PICU in a tertiary university hospital. Between June 2012 and June 2013, aclinical pharmacist and medical student observed the nursing care staff on weekdays duringthe preparation and administration of intravenous drugs. We analyzed the frequency and typeof preparation and administration errors and factors associated with errors.Results: Six hundred and three preparations in the adult ICU and 281 in the NICU/PICU wereobserved. Three hundred and eighty-five errors occurred in the adult ICU and 38 in the NICU/PICU. There were 5,040 and 2,514 error opportunities, with overall error rates of 7.6% and 1.5%,respectively. The total opportunities for error meant each single step of preparation and administrationthat was relevant for the drug. Most errors applied to the category “uniform mixing”(adult ICU: n=227, 59%; NICU/PICU: n=14, 37%). The multivariate logistic regression resultsshowed a significantly different influence of the “preparation type” for the adult ICU comparedwith the NICU/PICU with regard to the occurrence of an error. Preparations for adult patientsof the LCD type (liquid concentrate with diluent into syringe or infusion bag) were more oftenassociated with errors than the P (powder in a glass vial that must be reconstituted and dilutedif necessary), P=0.012, and LC (liquid concentrate into syringe), P=0.002 type.Conclusion: “Uniform mixing” was the most erroneous preparation step in intravenous drugpreparations in two ICUs. Improvement of nurse training and the preparation of prefilled syringesin the pharmacy might reduce errors and improve the quality and safety of drug therapy.$$leng 000773440 588__ $$aDataset connected to Lobid/HBZ 000773440 591__ $$aGermany 000773440 7001_ $$0P:(DE-82)006545$$aOrlikowsky, Thorsten$$b1$$eThesis advisor$$urwth 000773440 7001_ $$0P:(DE-82)014612$$aStoppe, Christian$$b2$$eThesis advisor$$urwth 000773440 7870_ $$0RWTH-CONV-219953$$iRelatedTo 000773440 7870_ $$0RWTH-CONV-240194$$iRelatedTo 000773440 909CO $$ooai:publications.rwth-aachen.de:773440$$pVDB 000773440 9101_ $$0I:(DE-588b)36225-6$$6P:(DE-588)1199210137$$aRWTH Aachen$$b0$$kRWTH 000773440 9101_ $$0I:(DE-588b)36225-6$$6P:(DE-82)006545$$aRWTH Aachen$$b1$$kRWTH 000773440 9101_ $$0I:(DE-588b)36225-6$$6P:(DE-82)014612$$aRWTH Aachen$$b2$$kRWTH 000773440 9141_ $$y2019 000773440 9201_ $$0I:(DE-82)537500-2_20140620$$k537500-2$$lLehrstuhl für Allgemeine Pädiatrie$$x0 000773440 961__ $$c2019-11-28T14:56:30.232565$$x2019-11-28T14:56:30.232565$$z2019-11-28T14:56:30.232565 000773440 980__ $$aI:(DE-82)537500-2_20140620 000773440 980__ $$aUNRESTRICTED 000773440 980__ $$aVDB 000773440 980__ $$aphd