h1

% IMPORTANT: The following is UTF-8 encoded.  This means that in the presence
% of non-ASCII characters, it will not work with BibTeX 0.99 or older.
% Instead, you should use an up-to-date BibTeX implementation like “bibtex8” or
% “biber”.

@PHDTHESIS{Hermanspann:773440,
      author       = {Hermanspann, Theresa},
      othercontributors = {Orlikowsky, Thorsten and Stoppe, Christian},
      title        = {{E}valuation of the medication process of intravenous
                      preparations in two intensive care units},
      school       = {Rheinisch-Westfälische Technische Hochschule Aachen},
      type         = {Dissertation},
      address      = {Aachen},
      reportid     = {RWTH-2019-11105},
      pages        = {1 Band (verschiedene Zählungen) : Illustrationen,
                      Diagramme},
      year         = {2019},
      note         = {Dissertation, Rheinisch-Westfälische Technische Hochschule
                      Aachen, 2019, Kumulative Dissertation},
      abstract     = {Purpose: To determine the type, frequency, and factors
                      associated with medication preparationand administration
                      errors in adult intensive care units (ICUs) and neonatal
                      ICUs (NICUs)/pediatric ICUs (PICUs).Patients and methods: We
                      conducted a prospective direct observation study in an
                      adultICU and NICU/PICU in a tertiary university hospital.
                      Between June 2012 and June 2013, aclinical pharmacist and
                      medical student observed the nursing care staff on weekdays
                      duringthe preparation and administration of intravenous
                      drugs. We analyzed the frequency and typeof preparation and
                      administration errors and factors associated with
                      errors.Results: Six hundred and three preparations in the
                      adult ICU and 281 in the NICU/PICU wereobserved. Three
                      hundred and eighty-five errors occurred in the adult ICU and
                      38 in the NICU/PICU. There were 5,040 and 2,514 error
                      opportunities, with overall error rates of $7.6\%$ and
                      $1.5\%,respectively.$ The total opportunities for error
                      meant each single step of preparation and administrationthat
                      was relevant for the drug. Most errors applied to the
                      category “uniform mixing”(adult ICU: n=227, $59\%;$
                      NICU/PICU: n=14, $37\%).$ The multivariate logistic
                      regression resultsshowed a significantly different influence
                      of the “preparation type” for the adult ICU comparedwith
                      the NICU/PICU with regard to the occurrence of an error.
                      Preparations for adult patientsof the LCD type (liquid
                      concentrate with diluent into syringe or infusion bag) were
                      more oftenassociated with errors than the P (powder in a
                      glass vial that must be reconstituted and dilutedif
                      necessary), P=0.012, and LC (liquid concentrate into
                      syringe), P=0.002 type.Conclusion: “Uniform mixing” was
                      the most erroneous preparation step in intravenous
                      drugpreparations in two ICUs. Improvement of nurse training
                      and the preparation of prefilled syringesin the pharmacy
                      might reduce errors and improve the quality and safety of
                      drug therapy.},
      cin          = {537500-2},
      ddc          = {610},
      cid          = {$I:(DE-82)537500-2_20140620$},
      typ          = {PUB:(DE-HGF)11},
      url          = {https://publications.rwth-aachen.de/record/773440},
}