TY - THES AU - Schneider, Hannah Sophia TI - Radiomics in der Mamma MRT: Klassifikation kontrastmittelaufnehmender Läsionen nach ihrer Dignität mittels zweier klassischer Machine Learning Algorithmen PB - Rheinisch-Westfälische Technische Hochschule Aachen VL - Dissertation CY - Aachen M1 - RWTH-2020-07774 SP - 1 Online-Ressource (IV, 66 Seiten) : Illustrationen, Diagramme PY - 2020 N1 - Veröffentlicht auf dem Publikationsserver der RWTH Aachen University N1 - Dissertation, Rheinisch-Westfälische Technische Hochschule Aachen, 2020 AB - In this doctoral thesis, the application of radiomic algorithms in Mamma MRI for classification of contrast-enhancing lesions is depicted. 1294 lesions out of 447 breast MRI examinations were manually segmented and 562 image features were extracted in total. These included shape, statistical and texture features from routinely acquired MRI sequences. Either histopathological analysis or a 2-year follow-up were used as target values, and for comparison with a radiological expert, lesions were grouped into BI-RADS® categories according to their prospective diagnostic reports. Correlation of the extracted features and the corresponding target values was performed by training and validation of two conventional radiomic algorithms - L1-Regularization and Principal Component Analysis. Though classification results were clinically acceptable (sensitivity 72 LB - PUB:(DE-HGF)11 DO - DOI:10.18154/RWTH-2020-07774 UR - https://publications.rwth-aachen.de/record/794608 ER -