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000799391 001__ 799391
000799391 005__ 20230209042924.0
000799391 0247_ $$2CORDIS$$aG:(EU-Grant)870294$$d870294
000799391 0247_ $$2CORDIS$$aG:(EU-Call)H2020-NMBP-BIO-CN-2019$$dH2020-NMBP-BIO-CN-2019
000799391 0247_ $$2originalID$$acorda__h2020::870294
000799391 035__ $$aG:(EU-Grant)870294
000799391 150__ $$aMIXed plastics biodegradation and UPcycling using microbial communities$$y2020-01-01 - 2023-12-31
000799391 371__ $$aAB Enzymes GmbH$$bAB Enzymes$$dGermany$$ehttp://www.abenzymes.com$$vCORDIS
000799391 371__ $$aUNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN$$bNUID UCD$$dIreland$$ehttp://www.ucd.ie$$vCORDIS
000799391 371__ $$aAGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS$$bCSIC$$dSpain$$ehttp://www.csic.es$$vCORDIS
000799391 371__ $$aForschungszentrum Jülich$$bForschungszentrum Jülich$$dGermany$$ehttps://www.ptj.de/$$vCORDIS
000799391 371__ $$aRWTH Aachen University$$bRWTH$$dGermany$$ehttp://www.rwth-aachen.de/cms/~a/root/lidx/1/$$vCORDIS
000799391 371__ $$aUniversity of Greifswald$$bUniversity of Greifswald$$dGermany$$ehttp://www.uni-greifswald.de/?L=1$$vCORDIS
000799391 371__ $$aBIOPLASTECH LTD$$bBIOPLASTECH LTD$$dIreland$$vCORDIS
000799391 371__ $$aCNRS - Institut des Sciences Biologiques$$bINSB$$dFrance$$ehttp://www.cnrs.fr/insb/$$vCORDIS
000799391 371__ $$aSOPREMA$$bSOPREMA$$dFrance$$ehttp://WWW.SOPREMA.FR$$vCORDIS
000799391 371__ $$aPGS PACIFIC GARBAGE SCREENING GMBH$$dGermany$$ehttp://www.pacific-garbage-screening.com$$vCORDIS
000799391 372__ $$aH2020-NMBP-BIO-CN-2019$$s2020-01-01$$t2023-12-31
000799391 450__ $$aMIX-UP$$wd$$y2020-01-01 - 2023-12-31
000799391 5101_ $$0I:(DE-588b)5098525-5$$2CORDIS$$aEuropean Union
000799391 680__ $$aThe continuing demand for plastic products, the lack of appropriate recycling and the ubiquitous pollution of the environment with plastic waste pose a global challenge. An ambitious vision and considerable efforts are required to change the traditional value chain of plastics to a sustainable one, based on biodegradable plastics.
In MIX-UP, plastic mixtures with five of the top six fossil-based recalcitrant plastics (PP, PE, PUR, PET, and PS), along with upcoming biodegradable plastics such as PLA and PHA, will be used as feedstock for microbial transformations, thereby generating a workflow that increases the recycling quota and adds value to poorly recycled plastics waste streams. Successive controlled enzymatic and microbial degradation of mechanically pre-treated plastics waste will be combined with subsequent microbial conversion to value-added chemicals and polymers by mixed cultures. We will optimize known plastics-degrading enzymes for high specific binding capacities, stability, and catalytic efficacy towards a broad spectrum of plastics polymers under high salt and temperature conditions by integrated protein engineering, and also isolate novel enzymes with activities on recalcitrant polymers. MIX-UP will also optimize the production of enzymes and formulate enzyme cocktails tailored to specific waste streams. Implementation of these enzymes, both in vitro and in vivo, enables stable self-sustaining microbiomes to convert the released plastic monomers selectively into at least six value-added products, key building blocks, and biomass. Any remaining material recalcitrant to enzymatic activity will be recirculated into the process after a physico-chemical treatment.
The Chinese-European MIX-UP is a multidisciplinary and industry-driven consortium that addresses the market need for novel sustainable routes to valorise plastics waste streams. MIX-UP realises a circular (bio)-economy and could be a viable alternative for mechanical and chemical recycling.
000799391 909CO $$ooai:juser.fz-juelich.de:881838$$pauthority$$pauthority:GRANT
000799391 909CO $$ooai:juser.fz-juelich.de:881838
000799391 970__ $$aoai:dnet:corda__h2020::f449d8f680a98975d9a2c11587489c59
000799391 980__ $$aG
000799391 980__ $$aCORDIS
000799391 980__ $$aAUTHORITY