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%0 Thesis
%A Talalwa, Lotfi
%T Charakterisierung und Experimentelle Validierung von 3D-druckbarem Elastomer-Polymer als Phantommaterialien für Hybride Medizinische Bildgebungstechnologien
%I Rheinisch-Westfälische Technische Hochschule Aachen
%V Dissertation
%C Aachen
%M RWTH-2022-00821
%P 1 Online-Ressource : Illustrationen, Diagramme
%D 2022
%Z Veröffentlicht auf dem Publikationsserver der RWTH Aachen University
%Z Dissertation, Rheinisch-Westfälische Technische Hochschule Aachen, 2022
%X The development of customized 3D models, as medical imaging phantoms for hybrid scanners, using porous polymers, is fundamentally challenging and interesting, at the same time, there is an increasing demand to produce 3D printed tools for various medical imaging techniques. These phantoms usually utilized as tools to test, assist, and monitor the performance of various medical imaging modalities, on a regular basis. This thesis investigated the suitability of different types of 3D printable porous filaments, for applications in medical research, i.e CT, PET, and MRI. To simulate the shape of different organs of the animals body, by varying 3D printing parameters, e.g infill densities, the perimeters and the infill structure, post-processing, and finishing of the printed models, and by assessting their influences on the reconstructed and analyzed image's contrast and quality. This leads us to perform various interesting experimental studies. Therefore, the characterizations of porous polymers were carried out using a dual extruder 3D printer and using many research technologies, e.g small-angle x-ray scattering instruments based on the intensity profiles acquired by using a CuKα radiation of wavelength 0.154 nm, PET scans using 18-F FDG and FET radiotracers, CT scans, besides the dielectric properties at a frequency range from 3 MHz-1.8 GHz, all results were verified using 3T MRI scans using 20 channel head coils with different MRI sequences. This thesis showed that the investigated polymers in this study is one of the potential candidates to construct various tunable 3D models, with good image quality and acceptable dimensional stability so far. Moreover, it is highly recommended to investigate other new printable materials that might have the ability to serve as phantom materials and can be used to mimic some properties of animals soft tissues and organs. The development of these materials are essential to construct dedicated man-made anthropomorphic phantoms.
%F PUB:(DE-HGF)11
%9 Dissertation / PhD Thesis
%R 10.18154/RWTH-2022-00821
%U https://publications.rwth-aachen.de/record/839762