h1

TY  - THES
AU  - Reisgen, Mara
TI  - Increased neutrophil granulocyte and myeloperoxidase levels indicate acute inflammation due to the exposure of zinc- and copper-containing welding fumes
PB  - Rheinisch-Westfälische Technische Hochschule Aachen
VL  - Dissertation
CY  - Aachen
M1  - RWTH-2023-07815
SP  - 25 ungezählte Seiten : Illustrationen
PY  - 2023
N1  - Dissertation, Rheinisch-Westfälische Technische Hochschule Aachen, 2023
AB  - This dissertation presents the results of a study aimed at investigating the impact of exposure to zinc- and copper containing welding fumes on leukocytes and myeloperoxidase (MPO), in light of known research demonstrating an effect on the human organism like increased C-reactive protein (CRP) levels subsequent to such exposures. In two distinct models, blood samples from male volunteers were analyzed before and after they were exposed to welding fumes: repeated exposure on four consecutive days, each lasting 6 hours and single exposures for 3, 4 or 5 hours each. An increase in neutrophil granulocytes and MPO was observed 24 hours after both, the single and repeated exposures lasting 6 hours. This increase is comparable to the CRP increase already described in the literature after exposure to welding fumes. This investigation points to the involvement of neutrophil granulocytes in metal fume fever and additionally demonstrates their mediating effects.
LB  - PUB:(DE-HGF)11
UR  - https://publications.rwth-aachen.de/record/963423
ER  -