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@PHDTHESIS{Han:977930,
author = {Han, Tianyu},
othercontributors = {Schulz, Volkmar Adolf and Stahl, Achim},
title = {{G}enerative modeling for medical image analysis},
school = {RWTH Aachen University},
type = {Dissertation},
address = {Aachen},
publisher = {RWTH Aachen University},
reportid = {RWTH-2024-00999},
pages = {1 Online-Ressource : Illustrationen},
year = {2024},
note = {Veröffentlicht auf dem Publikationsserver der RWTH Aachen
University; Dissertation, RWTH Aachen University, 2024},
abstract = {Radiology is undergoing a transformation with the
increasing integration of machine learning into medical
imaging. This promises enhanced diagnostic precision and
faster diagnosis. Yet, creating potent machine learning
algorithms for this domain often demands vast volumes of
labeled data. In intricate radiological scenarios,
annotating these images can be both time-intensive and
costly. To counteract these hurdles, we advocate for
unsupervised learning methodologies in medical imaging
analysis. We place emphasis on the deployment of a
self-supervised generative model. This model is tailored to
decipher latent temporal trajectories from longitudinal
radiographs of patients, thereby facilitating model-driven
forecasts regarding the emergence and evolution of
osteoarthritis. Further, we introduce an innovative paradigm
aimed at publicly sharing medical imaging data for algorithm
training. This ensures the safeguarding of sensitive patient
information. Alongside, we underline the imperative to
elevate the transparency of deep learning in a clinical
setting and bolster the algorithms’ resilience to
adversarial onslaughts. In essence, by capitalizing on
unsupervised learning strategies and pioneering ways to make
medical imaging data both accessible and secure, we stand on
the cusp of redefining radiological research, all while
elevating patient care outcomes.},
cin = {133510 / 130000},
ddc = {530},
cid = {$I:(DE-82)133510_20140620$ / $I:(DE-82)130000_20140620$},
typ = {PUB:(DE-HGF)11},
doi = {10.18154/RWTH-2024-00999},
url = {https://publications.rwth-aachen.de/record/977930},
}