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%0 Thesis
%A Krebs, Janina
%T Die Rolle des Fetuin-B im menschlichen Fertilisationsprozess
%I Rheinisch-Westfälische Technische Hochschule Aachen
%V Dissertation
%C Aachen
%M RWTH-2024-07681
%P 1 Online-Ressource : Illustrationen
%D 2024
%Z Veröffentlicht auf dem Publikationsserver der RWTH Aachen University
%Z Dissertation, Rheinisch-Westfälische Technische Hochschule Aachen, 2024
%X The thesis “The role of Fetuin-B in the process of human fertilization”, written by Janina Krebs, examines the influence of Fetuin-B on the fertilization. The thesis investigates the association between Fetuin-B and fertilization rates (number of fertilized eggs) during an ART-Therapy (assisted reproductive technology). More precisely, the author analyses Fetuin-B’s ability to act as a biological prognostic marker. An additional research question of the thesis is, if Fetuin-B is influenced by characteristics such as age, body-mass-index (BMI), nicotine consumption, primary or secondary infertility. Therefore, Fetuin-B levels were measured multiple times from 101 patients that underwent ART-therapy for the first time. ELISA-technique was used for subsequent analysis. The main result is that Fetuin-B significantly increases during successful fertilization (fertilization rate >25
%F PUB:(DE-HGF)11
%9 Dissertation / PhD Thesis
%R 10.18154/RWTH-2024-07681
%U https://publications.rwth-aachen.de/record/991096