Efficacy and safety of delgocitinib cream in adults with moderate to severe chronic hand eczema (DELTA 1 and DELTA 2): results from multicentre, randomised, controlled, double-blind, phase 3 trials

Bissonnette, Robert (Corresponding author) ; Warren, Richard B. ; Pinter, Andreas ; Agner, Tove ; Gooderham, Melinda ; Schuttelaar, Marie L. A. ; Crépy, Marie-Noëlle ; Stingeni, Luca ; Serra-Baldrich, Esther ; Baranowski, Keith ; Korn, Sofie ; Kurvits, Merle ; Plohberger, Ursula ; Strange Vest, Natacha ; Schliemann, Sibylle ; trial investigators (Collaboration author) ; Lynde, Charles (Contributor) ; Guenther, Lyn (Contributor) ; Sauder, Maxwell (Contributor) ; Bissonnette, Robert (Contributor) ; Rao, Jaggi (Contributor) ; Day, Isaiah (Contributor) ; Devani, Alim (Contributor) ; Metelitsa, Andrei (Contributor) ; Grewal, Parbeer (Contributor) ; Molin, Sonja (Contributor) ; Ruer-Mulard, Mireille (Contributor) ; Giordano-Labadie, Françoise (Contributor) ; Maillard, Hervé (Contributor) ; Reguiai, Ziad (Contributor) ; Bernier, Claire (Contributor) ; Leleu, Camille (Contributor) ; Seneschal, Julien (Contributor) ; Staumont-Sallé, Delphine (Contributor) ; Hubiche, Thomas (Contributor) ; Jacobzone, Caroline (Contributor) ; Khemis, Abdallah (Contributor) ; Crépy, Marie-Noëlle (Contributor) ; Worm, Margitta (Contributor) ; Bauer, Andrea (Contributor) ; Sell, Sabine (Contributor) ; Ekanayake-Bohlig, Swarna (Contributor) ; Pauser, Sylvia (Contributor) ; Buhl, Timo (Contributor) ; Schwinn, Andreas (Contributor) ; Eberlein, Bernadette (Contributor) ; Quist, Sven (Contributor) ; Bauer, Boris (Contributor) ; Peris, Ketty (Contributor) ; Rossi, Maria Teresa (Contributor) ; Fargnoli, Maria (Contributor) ; Naldi, Luigi (Contributor) ; Stingeni, Luca (Contributor) ; Ferrucci, Silvia (Contributor) ; Walecka-Herniczek, Irena (Contributor) ; Krasowska, Dorota (Contributor) ; Lesiak, Aleksandra (Contributor) ; Okuniewska, Aleksandra (Contributor) ; Pulka, Grażyna (Contributor) ; Dyczek, Malgorzata (Contributor) ; Kwiek, Bartlomiej (Contributor) ; Czajkowski, Rafal (Contributor) ; Myśliwiec, Hanna (Contributor) ; Mohandas, Padma (Contributor) ; Cliff, Sandeep (Contributor) ; Warren, Richard (Contributor) ; Cousen, Pippa (Contributor) ; Johnston, Graham (Contributor) ; Woolf, Richard (Contributor) ; Papp, Kim (Contributor) ; Adam, David (Contributor) ; Toth, Darryl (Contributor) ; Hong, Chih-Ho (Contributor) ; Turchin, Irina (Contributor) ; Niakosari, Firouzeh (Contributor) ; Poulos, Elena (Contributor) ; Rivers, Jason (Contributor) ; Ohayon, Jason (Contributor) ; Gooderham, Melinda (Contributor) ; Tjioe, Milan (Contributor) ; Rustemeyer, Thomas (Contributor) ; de Bruin-Weller, Marjolein S. (Contributor) ; Schuttelaar, Marie L. A. (Contributor) ; Molhoek, Judith (Contributor) ; Oosting, Bert (Contributor) ; Pinter, Andreas (Contributor) ; Kaspari, Markus (Contributor) ; Magnolo, Nina (Contributor) ; Sebastian, Michael (Contributor) ; Thaci, Diamant (Contributor) ; Schliemann, Sibylle (Contributor) ; Radny, Peter (Contributor) ; Leitz, Nicolas (Contributor) ; Tsianakas, Athanasios (Contributor) ; Yazdi, Amir Sadegh (Contributor)^RWTH* ; Kamstrup, Maria (Contributor) ; Sommerlund, Mette (Contributor) ; Zachariae, Claus (Contributor) ; Owczarek, Witold (Contributor) ; Dudra-Jastrzebska, Monika (Contributor) ; Reich, Adam (Contributor) ; Kowalska-Oledzka, Elzbieta (Contributor) ; Szepietowski, Jacek (Contributor) ; Poznanska, Maria (Contributor) ; Weglowska, Jolanta (Contributor) ; Aerts, Olivier (Contributor) ; Roquet-Gravy, Pierre-Paul (Contributor) ; Lanssens, Sven (Contributor) ; Castelijns, Francisca (Contributor) ; Scheers, Christelle (Contributor) ; Suys, Erwin (Contributor) ; Kint, Bernard (Contributor) ; Serra-Baldrich, Esther (Contributor) ; Carrascosa, José Manuel (Contributor) ; de la Cueva Dobao, Pablo (Contributor) ; Izu, Rosa (Contributor) ; Silvestre, Juan Francisco (Contributor) ; Coto-Segura, Pablo (Contributor) ; Fernández-Orland, Almudena (Contributor)

In
The lancet 404(10451), Seiten/Artikel-Nr.:461-473

2024

ImpressumLondon [u.a.] : Elsevier

ISSN1474-547X

Online
DOI: 10.1016/S0140-6736(24)01027-4
10.1016/S0140-6736(24)01027-4

Einrichtungen

1. Klinik und Lehrstuhl für Dermatologie und Venerologie (536500-2)

Dokumenttyp
Journal Article

Format
online, print

Sprache
English

Anmerkung
Peer reviewed article

Externe Identnummern
SCOPUS: SCOPUS:2-s2.0-85199867599
WOS Core Collection: WOS:001292856300001
PubMed: pmid:39033766

Interne Identnummern
RWTH-CONV-254183
Datensatz-ID: 1007806

Beteiligte Länder
Canada, Denmark, France, Germany, Italy, Netherlands, Spain, UK

Lizenzstatus der Zeitschrift