Pembrolizumab in combination with gemcitabine and cisplatin compared with gemcitabine and cisplatin alone for patients with advanced biliary tract cancer (KEYNOTE-966): a randomised, double-blind, placebo-controlled, phase 3 trial

Kelley, Robin Kate; Elias, Rawad; Edeline, Julien; Song, Tianqiang; Pelzer, Uwe; Kasper-Virchow, Stefan; Yasui, Hisateru; Ozyilkan, Ozgur; Li, Dongliang; Sinapi, Isabelle; Outlaw, Darryl; Ozguroglu, Mustafa; Finn, Richard S.; Goetze, Thorsten; Munoz Martin, Andres Jesús; Eatock, Martin; Asselah, Jamil; Wong, Chun Yin; Ryu, Hyewon; Kelley, Robin; Siegel, Abby B.; Cubillo Gracian, Antonio; Low, John; Gou, Hongfeng; Verdaguer Mata, Helena; de Carvalho, Ricardo Saraiva; Tam, Vincent; Sugimoto, Rie; Stein, Stacey; Finn, Richard; Tanasanvimon, Suebpong; Malhotra, Usha; Scott-Brown, Martin; Pan, Yueyin; Grasselli, Julieta; Joubert, Warren; Segovia, Ruben; Hubert, Ayala; Bordonaro, Robert; Hatoum, Hassan; Brandi, Giovanni; Ales Diaz, Inmaculada; Ying, Jieer; Kaen, Diego; de Groot, D. J. A.; Ozaka, Masato; Carballido, Marcela; Davis, Sarah; Petorin, Caroline; Zhao, Haitao; KEYNOTE-966 Investigators; Sookprasert, Aumkhae; Qin, Shukui; Milella, Michele; Hwang, Juneul; Burgoyne, Adam; Camandaroba, Marcos; Pezet, Denis; Cheng, Ashley; Salman, Pamela; Wan Isahk, Wan Zamaniah; Ho, Wang Kwong; Hao, Chunyi; Kim, Jong Gwang; Begbie, Stephen; Aubin, Francine; Berres, Marie-Luise; Wong, Yoke Fui; Park, Joon Oh; Ngamphaiboon, Nuttapong; Iseas, Soledad; Harputluoglu, Hakan; Peng, Chuang; Inanc, Mevlude; Yen, Chia-Jui; Juengsamarn, Jitlada; Liang, Houjie; McWhirter, Elaine; Starling, Naureen; Heinemann, Volker; Tortora, Giampaolo; Ben-Aharon, Irit; Yau, Thomas; Yanez Weber, Patricio; Tonini, Giuseppe; Lopez, Charles; Oh, Sang Cheul; Soparattanapaisarn, Nopadol; Tsuji, Akihito; Roohullah, Aflah; Li, Wei; Gillmore, Roopinder; Lim, Chun Sen; Tan, Ai Lian; Mizutani, Tomonori; Lee, Myung Ah; Borbath, Ivan; Wade, James; Diab, Maria; Kelleher, Fergal; Easaw, Jacob; Moniz, Camila; Jeyasingam, Vaishnavi; Kose, Fatih; Bai, Li-Yuan; Falcone, Alfredo; Chen, Xiaoming; Lee, Wai Man Sarah; Mizuno, Nobumasa; Valle, Juan W.; Su, Haichuan; Beri, Nina; Seufferlein, Thomas; Anand, Sumitra; Siena, Salvatore; Smolenschi, Cristina; Painemal, Claudio; Vogel, Arndt; Bai, Yuxian; Arslan, Cagatay; Chan, Stephen L.; Choi, Hye Jin; Kazemi, Ghazaleh; Collignon, Joelle; Geva, Ravit; Gbolahan, Olumide; Oksuzoglu, Berna; Lee, Choong-kun; Malka, David; Franke, Fabio; Yu, Wenchang; Yoo, Changhoon; Venerito, Marino; Bouattour, Mohamed; Wang, Lu; Chiu, Tai-Jan; Demols, Anne; Eskens, Fredericus; Jimenez Fonseca, Paula; Barajas, Olga; Satoh, Taroh; Yu, Li; Lee, Hyun Woo; Butthongkomvong, Kritiya; Stemmer, Salomon; Hsu, Chiun; Kinupe Abrahao, Ana Beatriz; Akce, Mehmet; Mendez, Guillermo; Suksombooncharoen, Thatthan; Bates, Susan; Haj Mohammad, Nadia; Yazici, Ozan; Schulze, Kornelius; Masi, Gianluca; Lee, Margaret; Victorino, Ana Paula; Chen, Jen-Shi; Geneser, Keri-Lee; De Vos, Judith; Tan, Chih Kiang; Sasaki, Mitsuhito; Gu, Shanzhi; Uribe, Rodrigo; Klümpen, Heinz-Josef; Geng, Zhimin; Ren, Zhenggang; Lam, Ho Ching; Nervi, Bruno; Furukawa, Masayuki; McDermott, Ray; Chan, Stephan Lam; Cao, Ke; Verslype, Chris; Furuse, Junji; Kochenderfer, Mark; Waldschmidt, Dirk Thomas; Lingerfelt, Brian; Gumus, Mahmut; Kanai, Masashi; Chen, Ming-Huang; Weschenfelder, Rui; Mao, Yimin; Liang, Tingbo; Power, Derek; Sasidharan, Rita; McCune, Steven; Wasan, Harpeet; Ueno, Makoto; Geboes, Karen; Yang, Xuezhong; Klumpen, Heinz; Chon, Hong Jae; Assenat, Eric; Le Sourd, Samuel; Kim, Jin Won; Macarulla Mercade, Teresa; Fernandez, Plinio; Alves, Gustavo; Yalcin, Suayib; Blanc, Jean-Frederic; Morales, Luisa

doi:1474-547X

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Pembrolizumab in combination with gemcitabine and cisplatin compared with gemcitabine and cisplatin alone for patients with advanced biliary tract cancer (KEYNOTE-966): a randomised, double-blind, placebo-controlled, phase 3 trial - RWTH-2026-02964

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